Hypertrophic chondrocytes are deeply involved in the growth of mammalian bones. Researchers find that these cells transform into multiple functional cell types, including those responsible for ...

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...

Osteoblasts derived from MSCs are cells required for bone formation. Oxidative phosphorylation produces a lot of ATP and other products including NAD+ and ROS. These factors play important roles in ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An ...

A newly discovered receptor switch that boosts bone growth could transform how we treat osteoporosis, by stimulating the body’s own bone-building machinery using a targeted drug and even mechanical ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...