As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, making people more susceptible to a variety of infections. To try to ...

The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

In human cells, DNA carries chemical or "epigenetic" marks that decide how genes will be used in different tissues. Yet in a ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialised immune cells. The discovery, published in ...

Human skin cells have been reprogrammed into heart valve cells and then used to successfully transplant a pig heart valve into a rodent, led by the research of a Northeastern University professor. The ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the brain is not static; neurons continually adjust the strength of their ...