Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

A large, multi-institution study led by a Brown University physician-scientist could have important implications for the development of new classes of cancer therapeutics.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

In vitro studies pinpoint signaling pathways that could be potential targets in oral squamous cell carcinoma treatments.

Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department ...

Plants form a critical model for understanding regulated cell death (RCD) as part of their sophisticated immune responses. In the ongoing evolutionary arms ...

Cancer drug resistance is the devastating reason that treatments fail and cancers metastasize, spreading to distant sites ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

African Swine Fever Virus, ASFV, Viral Entry, Host Cell Invasion, CD163, Siglec-1, Macropinocytosis, Endosomal Escape, Immune Evasion, Signaling Pathways Share and Cite: Marcelino, K.B. and Fang, G.J.