The plasma membranes of eukaryotic cells are not uniform and possess distinct cholesterol– and sphingolipid–rich raft microdomains that are enriched in proteins known to be essential for cellular ...

MHC class II molecules are of central importance to the adaptive immune system. MHC-class-II-mediated peptide presentation is essential for positive and negative selection of CD4 + T cells in the ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity.