This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

DNA has often been called “the book of life,” but this popular phrase makes some biologists squirm a bit. True, DNA bears our genes, which spell out the instructions our cells use to make ...

Two sets of ribosome structures have recently led to two different interpretations of what limits the accuracy of codon translation by transfer RNAs. In this review, inspired by this intermezzo at the ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

The genetic code is made up of a total of 64 base triplets or codons. At least one codon encodes the information for each of the 20 amino acids used in the synthesis of proteins during translation.

The genetic code is a set of instructions that direct the translation of DNA into 20 amino acids, the basic units of proteins in living cells. The genetic code is made up of codons, which are ...

Scientists have discovered a microbe that bends the rules of the genetic code. This organism, Methanosarcina acetivorans, uses a flexible translation process. One codon, UAG, traditionally a stop ...