Figure 2: FRQ activities in circadian feedback loops are impaired in the frq codon-optimized strains. Figure 3: FRQ protein in the codon-optimized strains is less stable and more sensitive to trypsin ...

Codon usage varies widely between species, between genes in a genome and between sites in a gene. Explanations for natural variation in codon usage fall into two categories: mutational and selective.

The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...