In recent years, large-scale RNA interference (RNAi) libraries that are designed to target complete genomes have been produced for multiple organisms. When arrayed in 96- or 384-well microplates, with ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Quick—if you had to guess, what would you think is most likely to end all life on Earth: a meteor strike, climate change or a solar flare? (Choose carefully.) A new statistical method could help ...