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iSCALE技术突破空间转录组学局限,实现大样本的超分辨率分析
本研究针对现有空间转录组(ST)技术成本高、分辨率低、覆盖区域小等瓶颈,开发了iSCALE方法,通过整合多区域ST数据和H&E图像特征,成功实现大尺寸组织样本的超分辨率基因表达预测和细胞级结构注释,为疾病机制研究提供了新工具。 在生命科学研究领域,空间 ...
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