The long slow trek of scientific progress is occasionally punctuated by great leaps and quick sprints, towards an obscure finish line. Much of this forward progress has been made possible by advances ...

Statistical gene mapping allows the approximate localization of disease susceptibility genes on the human gene map in the absence of any functional knowledge of such genes. After a brief introduction ...

Linear regression-based quantitative trait loci/association mapping methods such as least squares commonly assume normality of residuals. In genetics studies of plants or animals, some quantitative ...

Objective: The conventional affected sib pair methods evaluate the linkage information at a locus by considering only marginal information. We describe a multilocus linkage method that uses both the ...