The concept of paradigm shift was introduced and popularized by the American physicist and philosopher Thomas Kuhn in his 1962 book The Structure of Scientific Revolutions. Kuhn described a paradigm ...

I believe we face a major macro shift: a "higher for longer" inflation and interest rate era, redefining the economic and market landscape. This new regime targets around 4% inflation and strong ...

Traditional RCTs are often impractical for innovative therapies, especially in ultra-rare conditions or where long-term outcomes are needed. Regulatory bodies have adapted to innovative study designs, ...