Protein function prediction and annotation represent critical challenges in the post‐genomic era. As high‐throughput sequencing continues to generate vast amounts of protein data, computational ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

The latest short science news items from C&EN. Proteins are vital for life, involved in virtually every biochemical process that makes life possible. They comprise one or more amino acid chains ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum ...

Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique to humans.

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but ...

Proteins are among the most important molecular building blocks of life. They are chains of amino acids assembled in our cells by ribosomes, the molecular "protein factories" of our bodies. The ...