Extracellular signal-regulated kinase 5 (ERK5), a distinct member of the mitogen-activated protein kinase (MAPK) family, is increasingly recognised for its central role in transducing extracellular ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

The study revealed the small-molecule signaling system for mammalian cell-cell communication that combines super-sensitivity with a chassis-friendly, low-burden design, and demonstrated the system's ...