Sequence variation is particularly relevant to infectious pathogens that mutate in response to antimicrobial therapy. Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase ...

Figure 1: Three-dimensional structure of the TEN domain. The TEN domain has a mixed αβ structure made up of a core β-sheet, consisting of four short antiparallel β-strands, surrounded by seven ...

Cats are much more than just our four-legged companions; new research now explains how our furry friends could also aid the development of new drugs for HIV. Researchers have deciphered the structure ...

Amid the unprecedented challenges presented by the COVID-19 pandemic, a once obscure enzyme found itself in the spotlight: reverse transcriptase. As laboratories worldwide rushed to develop reliable ...