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生物通
1月
胎盘MATE1在鼠类中的特异性表达有助于解释不同物种间胎儿对二甲双 ...
二甲双胍能够轻易穿过人体胎盘。然而,据报道在大鼠中,二甲双胍的胎儿与母体血浆浓度比(F/M比值)低至0.057。本研究 ...
生物通
2月
胎盘MATE1在鼠体内的特异性表达导致了不同物种间胎儿对二甲双胍和1 ...
Metformin跨胎盘转运的物种差异主要由MATE1功能特异性介导,研究通过基因表达分析和药物转运实验发现,rat胎盘中MATE1高表达且 ...
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