An important flaw in the funding approach used by Canada’s public drug plans is highlighted by the findings of 2 articles related to the clinical value of direct oral anticoagulants (DOACs), published ...

Bell palsy is an idiopathic weakness or paralysis of the face of peripheral nerve origin, with acute onset. It affects 20–30 persons per 100 000 annually, and 1 in 60 individuals will be affected over ...

KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department. [1] [1] It is a clinical spectrum ...

Since late 2023, new outbreaks have been reported in Bolivia, Brazil, Peru, and Cuba, including among travellers returning to Canada and the United States. [1] [1], [2] [2] Malaria, Zika, dengue, and ...

Diagnosis and management of testosterone deficiency syndrome in men: clinical practice guideline ...

Acne is one of the most burdensome diseases globally. 1, 2 Its prevalence among those aged 12 to 24 years is estimated to be 85%, although it can persist beyond young adulthood despite treatment. 3 – ...

Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial ...

Background: Cancer surveillance data are essential to help understand where gaps exist and progress is being made in cancer control. We sought to summarize the expected impact of cancer in Canada in ...

Up to 0.3% of males will receive a diagnosis of anorexia nervosa in their lifetime. [1] [1] Affected males have a 6-times higher mortality rate than those in the general population. [2] [2] Stigma, ...

Bupropion abuse is a growing public health problem Although bupropion shares some structural and pharmacologic properties with amphetamine, early research suggested the drug did not produce any ...

Background: In 2002, the Belgian Act on Euthanasia came into effect, regulating the intentional ending of life by a physician at the patient’s explicit request. We undertook this study to describe ...

Smoking marijuana can increase clearance of some drugs Smoked marijuana increases the clearance of theophylline 40%. 1 Similar findings would be expected for other drugs metabolized by CYP1A2, such as ...